منابع مشابه
Phototherapy and photopharmacology.
The activation of 8-methoxypsoralen (8-MOP) by long-wavelength ultraviolet A light (UVA, 320-400 nm) induces the formation of interstrand cross-links in DNA. Psoralen plus UVA (PUVA) is widely used in the treatment of psoriasis, a hyperproliferative disease of the skin. A new psoralen plus UVA therapy has been developed in which the 8-MOP-containing blood of cutaneous T cell lymphoma (CTCL) pat...
متن کاملSyntonic phototherapy.
Clinical and basic research in the last decades showing the impact of light on cells, tissues, blood, circadian rhythms, and mood disorders has increased the acceptance of light as a healing agent. This article describes syntonic optometric phototherapy in hopes of stimulating interest and research to validate and expand its use. We are very grateful to Dr. Raymond Lanzafame, PMLS, Editor-in-Ch...
متن کاملTar troubles
Michael Hastings graduated in Marine Biology from the University of Liverpool in 1977, and remained at the Port Erin Marine Laboratory, Isle of Man, to conduct PhD work on tidal clocks and behavioural rhythms in crustaceans. After taking a post-graduate Certificate of Education in Manchester (1980), in 1981 he moved to the Department of Anatomy in the University of Cambridge as a post-doc to wo...
متن کاملPoly Tar
Downloa cer chemotherapy exploits limitations in repairing DNA damage in order to kill proliferating nant cells. Recent evidence suggests that cancers within and across tissue types have specific defects A repair pathways, and that these defects may predispose for sensitivity and resistance to various s of cytotoxic agents. Poly (ADP-ribose) polymerase (PARP) and BRCA proteins are central to th...
متن کاملMole Tar
Download wth factors and many oncogenes activate the lipid kinase phosphoinositide 3-kinase (PI3K), ing a signaling cascade that includes the protein kinases AKT and target of rapamycin (TOR). The AKT/TOR signaling pathway is a significant contributor to disease in various human cancers, includmatologic malignancies. Here we discuss different strategies to inhibit TOR for the treatment of ia, l...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1978
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12515109